The Role of Androgen Receptor Expression in Prostate Adenocarcinoma

Prostate cancer is one of the most common worldwide, where South Sulawesi included in four provinces with highest prevalence prostate Indonesia. Laboratorium Sentra Patologia Makassar (SDPM) stated that cases continue to rise each year. Androgen receptor (AR) plays a role growth and differentiation male urogenital structures, both under normal neoplastic conditions, condition caused by mechanism AR pathway which undergoes changes development progression lesions, benign malignant. receptors are generally found evenly distributed nuclei glandular stromal cells hyperplasia vary widely cancer. These inventions show inhibitors used treat adenocarcinoma inhibiting androgen synthesis. Assessment expression can be determining therapy predicting success hormonal so prognosis disease better. This study conducted learn more about grading. The type this research an observational analytical cross-sectional methods. Samples taken based on consecutive sampling as many 77 respondents. There significant difference between score histopathological feature WHO Grup Grade (p<0,001). In conclusion, there correlation could important marker grading progression
 Keywords : (AR); adenocarcinoma;